Pain reliever, nasal decongestant, antihistamine (antihistamine in nighttime only). Day: Non-drowsy. Contains 2 Medicines: Headache - acetaminophen; sinus pressure, nasal congestion - phenylephrine HCl. Night: Contains 3 Medicines: Headache - acetaminophen; sinus pressure, nasal congestion - phenylephrine HCl; runny nose - Chlorpheniramine maleate.